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Dry Skin has Met its Match with SENTÉ’s HSA

As the skin ages, we see changes in and on our skin that reflect our skin type, our skin concerns and how well we have addressed those concerns over the years. For those with dry to very dry skinaging skin is more than fine lines and wrinkles. Chronic inflammation and dehydration are significant factors at the root of skin aging. We find that we need ever-increasing surface moisture supported by deep, lasting hydration in order to maintain our smooth, fresh glow. While the skin has the natural ability to maintain hydrationthat becomes reduced with time and age.  

When we think about dry skin, we see skin with an impaired epidermal barrier that causes it to become more sensitive and reactive to environmental factors and irritants.  This becomes a vicious circle – dryness leads to impaired barrier - impaired barrier leads to dryness, which leads to redness and increased sensitivity.  Dry skin shows up on the face as decreased elasticity, rough skin texture, wrinkling and visible redness – signs of aging that we want to address with our skin care regimen, but for those with dry skin, even the best regimen can fall short of the goals.  

We often work to remedy that with heavier, thicker moisturizing creams. Unfortunately, a heavier cream does not necessarily equate to long-term improvements in hydration or moisturization, so the search for that perfect balance of long-lasting hydration and immediate, soothing moisture continues.  

How does the skin maintain its own healthy hydration levels? One of the most biologically active hydrators in the skin is Heparan Sulfate (HS), a naturally occurring complex sugar found within our skin that is essential to maintaining skin healthHS supports deep hydration, reduces water loss and promotes skin repair by protecting collagen and elastin fibers from degradation. HS is vital to healthy, hydrated skin, but as we age the abundance and production of HS decreases significantly, which leads to the changes we see on our skin including increased dryness, redness and sensitivity. Further, the lipid content of aged skin is reduced by as much as 65% with sebum production decreasing as much as 60%. Studies have shown that the aged stratum corneum (the uppermost layer of cells on the skin surface) displays more than a 30% reduction in total lipid content in comparison to the young stratum corneum.  

This is where SENTÉ’s Dermal Repair Ultra-Nourish enters the picture. This revolutionary lipid replenishing cream combines Heparan Sulfate Analog (HSA) and a unique blend of lipids to nourish and smooth skin while improving the appearance of fine lines and wrinkles, redness, and skin tone and texture for soft, supple, and radiant skin 

Heparan Sulfate Analog (HSA) SENTÉ skincare’s unique, proprietary ingredient is a key technology in Dermal Repair Ultra-NourishHSA targets the underlying causes of inflammation and supports the skin’s natural ability to repair itself. It is clinically shown to deliver deep hydration, decrease visible redness, and improve the appearance of fine lines and wrinkles 

SENTÉ’s Dermal Repair Ultra-Nourish is uniquely formulated for dry to very dry and sensitive skin to help improve the signs of dryness with a combination of ingredients that support long-lasting deep hydration and moisturization. In addition to patented HSA, Dermal Repair Ultra-Nourish adds a lipid blend that naturally mimics the skin’s epidermal lipids to restore the skin barrier with a balanced concentrate of unsaturated fatty acids, skin-identical ceramides and ceramide precursor.  

When used twice a day as directed in a clinical study, 100% of subjects said their skin felt nourished after using Dermal Repair Ultra-Nourish for 8 weeks. 90% agreed that it provided long-lasting hydration and moisturization. 79% said the product made fine lines and wrinkles look less visible at 8 weeks.  


Reaching and maintaining our facial rejuvenation goals is often an artful combination of skin care products, in office procedures including injectables, chemical peels and laser treatments. Managing a skin care regimen between those procedures is not difficult, but does often present questions. How often have you forgotten which product to stop using before a laser treatment, or when you can start using it again after a treatment? The ideal is to be able to continue as much of your regimen as possible before, between and after in-office procedures. With this knowledge, SENTÉ tested Dermal Repair Ultra-Nourish with non-ablative laser treatments, microneedling and chemical peels. In that case study, 85% of the subjects who used the product after their treatments said that their skin felt immediately moisturized and hydrated. 100% of subjects said that Dermal Repair Ultra-Nourish felt soothing when used after their treatment.  

With this amount of hydration and moisturization, we might expect a heavy cream, but not in this case! Great skin care comes in many forms, but SENTÉ knows that “heavy cream” does not solely guarantee results. Instead, this luxurious cream combines powerhouse HSA with replenishing lightweight lipids to support the skin barrier. The result is a soothing, refreshing water in silicone emulsion. When applied to the skin, you can feel this nurturing cream break into a slightly lighter, cooling and soothing veil of moisture your skin will love.  

Beauty is in the details! Further adding to the appeal of this luxurious cream is the packaging –  an airless pump jar that protects the product from contamination – just press down and you are rewarded with a measured, consistent dose for every single application.  

An improved skin barrier helps to prevent water loss from the skin and protects the skin from environmental factors that lead to further dryness and sensitivity. Adding Dermal Repair Ultra-Nourish to skin care regimen can help support deep-hydration and long-lasting moisturization to help calm sensitive skin, decrease the appearance of visible redness and fine lines & wrinkles, smooth rough texture and enhance the skin tone for a more glowing, youthful appearance